Intracellullar Signaling

The research group Intracellular Signalling of the Department of Biochemistry and Molecular Biology, Inmunology and Organic Chemistry of the Faculty of Medicine is focused on the study of the cellular signalling of angiotensin II through vascular endothelium. Thus, past and present studies of this group are of interest for companies from the health sciences sector and in particular for chemical and/or medical laboratories working on pharmacological compounds targeting the cardiovascular system. The group was founded in 1995 and consists currently of 6 members with an extensive experience in research and teaching. One of the most recent research projects focused on the action mechanisms of anti-tumour pharmacological compounds on proliferation and migration cellular process, as well as the signal-pathway implied.

Research Topics

• G-protein-coupled receptors. - Molecular characterization. - Intracellular signalling.
• Muscarinic acetylcholine receptors. ? Signal-pathway.
• Receptors and mechanism of action of angiotensin II. ? Signal-pathway.
• Apoptosis, proliferation, growing and migration cell.

Scientific-Technical Services

• Advice about the research topics.
• Training on intracellular mechanism of action.