HUMAN ANATOMY AND EXPERIMENTAL EMBRYOLOGY CTS1177

Description

The group studies the cellular and molecular mechanisms that regulate embryonic development,tissue homeostasis, and responses to injury, with a particular focus on the cardiovascular and nervous systems. The researchers have made previous contributions in the field to understanding coronary vessel formation, the identity and plasticity of cardiac endothelium, the role of the epicardium in cardiac development and repair, as well as the molecular mechanisms underlying neurogenesis and neurological disease. To address these questions, the group combines experimental models of development, regeneration, and pathology with advanced methodologies in molecular biology, genomics, single-cell transcriptomics, bioinformatics, microscopy, and three-dimensional tissue analysis.

Research Topics

Cardiovascular development and coronary vessel formation.
Angiogenesis and vascular remodeling.
Cardiac regeneration and tissue responses to injury.
Genetic, epigenetic, and post-transcriptional regulatory mechanisms controlling development and tissue repair.
Neurogenesis, associated diseases, and transcriptomic and genomic analyses using experimental models of development and regeneration.

Scientific-Technical Services

Histological analysis of embryonic, adult, and injured tissues.
Genomics studies, single-cell transcriptomics, and bioinformatic analysis of omics datasets.
Advanced microscopy analysis, three-dimensional tissue analysis, and vascular characterization.
Cell culture techniques and experimental models of development.